Burden associated with AF, measured as disability-adjusted life-years, increased by 18.8% (95% UI, 15.8–19.3) in men and 18.9% (95% UI, 15.8–23.5) in women from 1990 to 2010. The estimated number of individuals with AF globally in 2010 was 33.5 million (20.9 million men and 12.6 million women ). Of 377 potential studies identified, 184 met prespecified eligibility criteria. We systematically reviewed population-based studies of AF published from 1980 to 2010 from the 21 Global Burden of Disease regions to estimate global/regional prevalence, incidence, and morbidity and mortality related to AF (DisModMR software).
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